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I am using FindMarkers() between 2 groups of cells, my results are listed but i'm having hard time in...
Asked on 10/03/2021
1 answerI have around a hundred Fasta files (and will collect several thousand) with DNA sequences and +50x coverage. What is a recommended method to construct a phylogenetic tree? Solutions in...
Asked on 10/03/2021
4 answerOn my merged seurat object of 6 samples, when I use the split.by function in tandem with the Dimplot/UMAP plot, all six samples are displayed in series along a commonly...
Asked on 10/03/2021
1 answerI apologise for very basic question but I am very new to biology and have very specific knowledge of this field, I am currently working on Bioinformatics in my machine...
Asked on 10/02/2021 by Pragati Bhingare
0 answerIn creating a parser for the UniProt flat file uniprot_sprot.dat (directory) in the manual for the comments POLYMORPHISM there are listed patterns for alleles,...
Asked on 10/01/2021 by Guy Coder
1 answerHow would one determine the significance of a variable in a glm model? If I, for example, have a dataframe like seen below, how would I determine if the origin...
Asked on 09/30/2021 by RMM
2 answerFor the differentially expressed genes analysis, is it possible to check for DEGs based on the levels already identified in the object? For example, my dataset contains cells from 11...
Asked on 09/30/2021
1 answerIn each iteration of the neighbour-joining method of phylogenetic trees construction, after joining the nearest neighbours the (additive) distance matrix $D_{m times m}$ is recomputed as $$Q_{ij} =...
Asked on 09/28/2021 by Gogis
2 answerI'm hoping to quantitatively show differences in total RNA expression for a gene in a cluster of interest between different experimental groups. My exported average RNA values for each experimental...
Asked on 09/27/2021 by user9283
2 answerIn order to define which cell is of which type we need to identify a set of rules, for instance neurons should express one of the following: Thy1, Rbfox3, MAP2,...
Asked on 09/27/2021
4 answerGet help from others!
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