Is this image, taken about 1900, actually from Nuremberg?

I would suggest asking the Nuremberg Municipal Museums about this image or others tagged as Nürnberg.

Local museums are often interested in receiving such images taken by visitors since sometimes angles, viewpoints or a timeframe may complement their existing collections.

Based on @Arthur'sPass answer, which looks to me like a realistic candidate, the details on the right of your image might be of interest to a local museum in Zürich.

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Nuremberg Municipal Museums
Direction and Administration
Hirschelgasse 9-11
90403 Nuremberg Tel. +49 (0)911 231 - 54 21
Fax +49 (0)911 231 - 54 22

Florian Dierl M.A.
Department Head, Culture of Remembrance

[email protected]

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Sources:

• Nuremberg Municipal Museums

The church would appear to be the Grossmünster in Zürich.

^{New In Zürich}

The towers are quite distinctive, and the tip of the spire at the rear of the church (seen here between the towers) is just visible in your photo to the left of the left tower.

The building in the foreground of your photo - the Haus zum Rüden* - appears to the left in this image, and has a new roof.

The building to the right of your photo also appears in this image, next to the bridge.

There are what appear to be power lines suspended above the street, and tramlines set in the roadway. This would date the photograph to no earlier than 1894 when the first electric tramway opened in Zürich (source:Trams in Zürich).

Here is a screenshot from Google Maps:

^{* Thanks to @tuhuwawohu for the name of this building}