Storage Spaces Direct and Virtualization Architecture

I’m trying to figure out the best way to architect a 2 node fail over cluster with the Hyper V role installed. I can really use some input and suggestions from others who have already been down this road.

All in, I have a 4 physical machines with Datacenter 2019 installed on each. On machine 1 and 2 I have installed 1 VM each and clustered them together as a network load balancer. This work great, no problems here.

On machines 3 and 4 I want to create a Storage Spaces Direct Fail Over Cluster. On these 2 machines I also want to virtualize many services in VM’s. Sql Server, A File Server, Email Server etc.

What I am not grasping is as follows. Should I create the Storage Spaces Direct Failover cluster on the Host level or at the Hyper-V VM level? Obviously I need the data replicated across both machines should one machine go down.

I am not sure what the best approach here is.

Thanks in advance.