Anime where the main character's brother sacrifices himself by driving a missile or ship to its explosion

Please help me identify an anime which I forgot the name of. All
I can remember is a scene about the brother of the main character sacrificing himself by driving a missile or ship to a place in order to explode, and a woman trying to stop him but he locks the door. She tries to identify him by saying, “Are such and such?” but he doesn’t reply, then she leans on the door and starts crying, as he replies “Take care,” or something to that extent.

• It was in Japanese, subtitled in English
• I don’t remember the year exactly but I’m sure it’s not before 2005
• The setting was in a spaceship (It’s not Spaceship Yamato)