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Interpreting FURA depolarization/calcium assay

Psychology & Neuroscience Asked on December 2, 2020

I did a depolarization experiment that compared a mock-treated cell line with a treated line. One part of the results are easy to interpret: Treatment resulted in lower 350/380 ratios along the length of the response curve. That’s easy, the treatment probably reduced calcium transport. However, in addition to this, the treatment also significantly shifted each inflection in the curve earlier in number of cycles. How could this be interpreted?

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