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What fluids are in effusions caused by anticoagulant (constituent of rodenticide) poisoning?

Pets Asked by Henry Stone on April 24, 2021

(moved from medical exchange)

ACR rat poisons use anticoagulants to cause internal bleeding and thus death in rodents. If used improperly, poisoned rodents may pass the poison on to predators, including local pets. One possible symptom I read about is effusion (internal fluid ‘leaks’) as internal bleeding stays in body cavities. Multiple articles describe processes of using anticoagulants under lab conditions to obtain plasma. Does this mean that abdominal fluids in a pet from ingesting ACR rat poison would be mainly plasma, as opposed to ‘full blood’, and thus clear/yellow instead of red?

One Answer

Anticoagulants are commonly known as "blood thinners". They would be used to avoid the blood getting thicker and "clumping". For example this is useful for people that get thrombosis quickly, or people who could not move some time, for example after surgeries.

The use of Anticoagulants as poison against rodents uses this effect with a higher dose. The rodents will die (even days after eating the poison) by the smallest wound, because it will not stop bleeding. Modern poisons combine a second substance, causing internal wounds, so the rodent can not carry the poison to rodent-eating-predators.

To obtain blood plasma, the blood needs to be taken from the organism. By contact with the air, the blood starts to thicken and clumping. To avoid this, the Anticoagulants will be added, until the process of separate the plasma from all other natural blood-parts is successful finished.

So no, the internal fluids in the rodents will approximately not be yellow or clear. But I had no occasion until now, to confirm my guess at any poisoned rodent.

sources:

Answered by Allerleirauh on April 24, 2021

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