Can a bad timing chain result in only a single cylinder misfiring?

The question title should be pretty self explanatory. I have a 2002 Nissan Maxima which began idling and accelerating really poorly (seemingly out of nowhere) a few days ago while I was driving home from work. Plugged my OBD scan tool once I got home into its port and got back the code P0306 for a misfire in cylinder six.

I’ve tried to remedy the problem myself, thus far to little success; I have:

1. Replaced the spark plug in the faulty cylinder. Really glad that cylinder six isn’t behind the intake manifold.
2. Added fuel injector cleaner into my gasoline – maybe the problem is a dirty fuel injector?

I’m going to replace the ignition coil on the sixth cylinder soon since it seems like neither changing the spark plugs nor adding fuel injector cleaner has done anything – still getting poor idle and acceleration, and the gas mileage is tanking; hopefully it does. If not, I’ll be at the end of my DIY ability, and off to the mechanic it’ll go.

As in the title – is it possible for a timing chain problem to cause only one cylinder to misfire? My vague – and admittedly not great – intuition of how the timing chain synchronizes the camshaft and crankshaft tells me that I’d probably be experiencing problems in more than just one cylinder if I do have a timing chain problem.