Partitioning a list to several depths

I an aware of the Partition command which partitions a list into sublists. I’m curious as to whether there is an efficient way to partition a list several times over in one step. For example, can I turn the list

{1,2,3,4,5,6,7,8}

into the list

{{{1,2},{3,4}},{{5,6},{7,8}}}

through one use of the Partition command instead of two (or indeed any command). In actual fact, I’ll be going to a list of many levels of nested lists, which is why I’m keen to know the answer. Thanks in advance for any help.