Drawing on screen outside notebooks

Is there a way to display (animated) graphics outside of Mathematica notebooks, i.e., in a specified rectangle on the screen? I can imagine that one way to achieve that is by creating a notebook without borders, menu, or any other elements, and configuring it such that it stays always on top. Can this be achieved?

Update: I wonder whether AttachCell or other functions offer enough control to create a rectangular canvas (no window border or window elements) that stays always on top, allow control over transparency, and possibly hide the mouse cursor when it is moved over the "window" region. Think of something like a splash screen displaying an image with transparent regions for example. I agree that this is possible with Python/Tkinter for example but I am wondering how much of such detailed control is exposed in Mathematica.