Will a nest work for my hvac system

Nests have no trouble with heat pumps

A simple, single-stage heat pump like yours shouldn't be an issue for a Nest, even the stripped down E model. Your wiring goes as follows:

• Red to R or Rc
• Blue to C
• White to AUX if present, or W1 if not
• Yellow to Y1
• Green to G
• and Orange to O/B

Just remember to set your Nest up for a heat pump and set its O/B setting for an O wire if it isn't set that way already, and you should be good to go.