call opcode gas consumption on a non EOA address depends if the addres is "new" or not

I have the following contract, reduced to the minimum for testing reasons:

pragma solidity ^0.6.11;

contract PackedMultiplexer {
    function multiTransfer(address  _address1, uint _amount1, address  _address2, uint _amount2) payable public
    {
        assembly {
            pop(call(2300, _address2, _amount2, 0, 0, 0, 0))
            pop(call(2300, _address1, _amount1, 0, 0, 0, 0))
        }
    }
}

Now, I generate 2 new private keys.

I get 2 new public addresses 0x0c73c24c841ddDF2d476E7E2C1552Ea04364cc9A and 0xC16F1C0241B1204BC123650CfCb3A03046F2d91C, previously unknown to the network. Then I call the contract with those addresses and some random (constant) value for the amounts.

I get a first TX which consumes 87,191 gas.

I call a second time the contract with exactly the same parameters and get a second TX which consumes 37,191 gas.

My question: why is the gas consumption of the first execution of the contract and the second execution is different? It seems to me in both cases the same code is executed? What am I missing?

As you can see in the debugger, the first TX call opcodes consumes 37000 gas each; the second TX call opcodes consumes 12000 gas each. Why is that? How can I prevent the 37000 gas consumption?

(Note: the question holds true if you replace 2300 (first argument of call) in the code by gas() or 0.)