"Departed" or "departed from" before place/object?

I’m working on an essay and the first line of my introductory paragraph currently reads as:

Too many times, when sitting in an English classroom, have bitter
groans departed the lips of around twenty students when
Shakespeare’s name is mentioned.

This probably seems like a very facile question, but it’s somewhat confusing to me; the main definition of “depart,” according to the dictionary, is “to leave, typically in order to start a journey.” However, when reading, the word is often formatted such so that “from” is put in front of it, right before the area of question–– i.e., “he departed from his home in Alsace.” In this case, when referring to that definition, doesn’t it translate to “he left from his home in Alsace”? Wouldn’t “he departed his home in Alsace” (“he left his home in Alsace”) be more suitable and also less wordy? Are both usages grammatically correct?