Efficiency of propeller with Wind perpendicular to rotation axis

If the wind is near perpendicular to the propellers axis it will make it turn and creat lift. It is called a gyrocopter. Usually, another fan on the back provides the thrust and the big near-horizontal disk creates the lift.

But if you position a propeller in the exact perpendicular wind it loses the lift and will stall.

Unless one designs a custom profile blade specifically designed for maintaining lift under wind coming from a tangent plane. But even then building directional control, authority, efficiency is a different ballpark.