Passing tuples (key, value) into parameterized SQL query in Python

Generally speaking, you need a string to be executed that contains placeholders to accept the values contained within the tuple. Also, what you are calling your "tuple" is actually a Python dictionary, but that isn't a problem.

From the sqlite3 documentation, we can see there are two ways to correctly use the execute() method:

an example command is given as:

# This is the qmark style:
cur.execute("insert into people values (?, ?)", (who, age))

# And this is the named style:
cur.execute("select * from people where name_last=:who and age=:age", {"who": who, "age": age})

And the second example, the named style is exactly what would work with your situation. You can try the following, using the keys of the dictionary as the named placeholders:

cmd = """insert into YOUR_TABLE values Marke=:Marke, Kilometerstand=:Kilometerstand, Erstzulassung=:Erstzulassung, Kraftstoffart=:Kraftstoffart, "Leistung (PS)"=:"Leistung (PS)", Getriebe=:Getriebe"""
cur.execute(cmd, your_dictionary)

So each of the keys of your dictionary matches the name of the corresponding column in the target table.

Notice that I put the entire cmd in triple " to make a string literal that can itself contain the " character. I think it will be required, because you have a column name in your table that contains a space: Leistung (PS).