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Why do most negatively charged phospholipids concentrate in the inner leaftlet?

Biology Asked by Natdanai Boss on January 24, 2021

Due to the asymmetry of the lipid membrane, negatively charged phospholipids such as phosphatidylserine, phosphatidylinositol are concentrated in the inner leaflet, creating a different charge distribution between the two leaflets.

Why do most of the negatively charged phospholipids concentrate in the inner leaflet?

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