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types of cells in a pharyngeal specimen

Biology Asked on March 15, 2021

I would like to ask what type of cells should someone expect in a pharyngeal smear, in a person, who is infected with a viral infection. Thank you a lot!

One Answer

The tissue in the pharynx include:

Stratified squamous epithelium & mucus-producing glands.

However other cells that could be found would be other types of bacterial, is this what you're referencing?

Commonly scientists start with a gram stain to determine the classify the bacteria.

Gram+ bacteria have cell walls composed of thick layers of peptidoglycan. Gram+ cells stain purple when. Gram- bacteria have cell walls with a thin layer of peptidoglycan. Gram- bacteria stain pink.

The microbiome of a human consists of 100,000 billion bacteria. Therefore there are many types. E.g. Prevotella has been shown to be the most common type of bacteria in the human pharynx.

In a pharyngeal smear you would expect to find Stratified squamous epithelium, mucus-producing glands, bacteria and if a virus is present. Viral particles. This can be determined by RNA or DNA analysis.

E.g. COVID-19 is an RNA virus. If PCR analysis was completed on a sample obtained from a pharyngeal smear then we could confirm the presence of the aforementioned mammalian cells, bacteria and viral genetic material.

Answered by Andrew on March 15, 2021

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