How to find the origin of each Single Nucleotide Variants (SNV) in child when having variant call data for both parents?

Question

I am working with a trio (Mom, Dad, Child). I have variant call data for all three. Now I want to know each SNV in the child comes from which parent?
Is there any tool that could help me to achieve this goal?
Many thanks,
Vahid.

Daniel · Answer

If a SNP is present in a child it is also present in at least one of the parents (except for de novo mutations which are fairly rare). So just check which parent has which polymorphism. For a question like that you would write a script yourself to check that.

Answered by Daniel on January 18, 2021

How to find the origin of each Single Nucleotide Variants (SNV) in child when having variant call data for both parents?

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