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Cell-autonomous viral defense involving oxidative burst?

Biology Asked by John Wentworth on March 1, 2021

I’m looking for a mechanism by which a cell detects a virus (probably a retrovirus) within itself, then triggers an oxidative burst in response. This should all happen within the cell itself, independent of any immune-specific cells outside. Ultimately interested in humans, but any pointers whatsoever would help.

One Answer

So, the cell may trigger an oxidative burst in response to pathogen (not specifically virus).

In case of retroviruses, they are hard to detect for the cell (example HIV) as they use the cell machinery for replication and can also stay in inactive latent state thereby not triggering immune response.

Hope you found your answer. Thank you and good day.

Answered by user60732 on March 1, 2021

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