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? What meaning do positive and negative values have in the centroid plot for genes?

Bioinformatics Asked by homa taha on January 25, 2021

I was working with a dataset containing genes. The central plot of the model after using "shrunken centroid" is like the following picture:

I noticed that they can all be negative together, is it true in general? and what does it mean when a gene has a negative value?

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