Bioinformatics Asked on July 23, 2021
How can I find ligands of receptors (or vice versa)?
For example, I want to find the receptors of IL-8 (CXCL8).
CellPhoneDB is a publicly available repository of curated receptors, ligands and their interactions.
The interactions can be searched or downloaded.
Correct answer by Peter on July 23, 2021
Have you tried STRING?
It's a publicly available protein-protein interaction database, so it won't be a complete picture.
Ingenuity Pathways Analysis (IPA) is really nice but is a paid service. Ask your institution if they have a license for one.
Answered by Yuka Takemon on July 23, 2021
CellTalkDB is another option for a searchable ligand-receptor database. According to the webpage it is curated from other databases and the literature. Details are available in the publication.
Answered by Tapper on July 23, 2021
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