What does twisted.internet.error.ConnectError mean when I connect to a Landscape server?

I set up a handful of systems in landscape over the last week.

However, when I went to set up a handful more today, I recieved the following error message:

Request a new registration for this computer now? [Y/n]:
Traceback (most recent call last):
Failure: twisted.internet.error.ConnectError: An error occurred while connecting: 2: No such file or directory.

What is going on?

chown landscape:root /etc/landscape/client.conf
chmod 600  /etc/landscape/client.conf