Which crosspath is better overall for a 4-0-0 alch

So, a bit of backstory: I’ve been using 4-2-0 alchs for buffing because when you get perishing potions, it buffs brews and stims, but every YouTuber I’ve seen uses 4-0-2 alchs for buffing because it throws them out more often. so I’ve been wondering if one is better. 4-2-0 is quality over quantity and 4-0-2 is quantity over quality, so which is generally better?

by the way, perishing is better for 5-0-0 alchs because the buffs are permanent so why would you need to throw them faster if the potions are permanent.