Opening Esri Personal Geodatabase (*.mdb) using QGIS?

If you have installed a 64-bit version of QGIS on Windows and you find that Personal GeoDatabases (*.mdb) no longer work for you, then this solution might apply; I'm on QGIS 2.8.1 rather than 2.6, but I assume that the issue and thus the solution is the same.

The underlying issue relates to this GDAL bug: Problem reading MDBs (64-bit)

Step 1

Download the 64-bit version of the ODBC driver: Microsoft Access Database Engine 2010 Redistributable

If you don't have a 32-bit version of office installed you can just run the executable. If however you do have a 32-bit office installation you will need to run the executable from a command prompt using the /passive option

Step 2

Locate the qgis.bat file (mine is in C:OSGeo4W64binqgis.bat for example).

Add the following two lines:

set OGR_SKIP=ODBC
set PGEO_DRIVER_TEMPLATE=DRIVER=Microsoft Access Driver (*.mdb, *.accdb);DBQ=%%s

Step 3

Open QGIS and drag the mdb file onto your workspace

Voila!

The solution proposed works fine also on windows 10. Only a further suggestion for adding the two line to the qgis.bat file.

The two line are setting. So it is important to add the lines before the start of the command.

Probably it is undestood but if you are not careful, there is a risk of being mistaken.

Provided you have successfully installed Microsoft Access Database Engine 64 bit, you can:

Method 1 (works with QGIS 2)

add the following two lines:

set OGR_SKIP=ODBC
set PGEO_DRIVER_TEMPLATE=DRIVER=Microsoft Access Driver (*.mdb, *.accdb);DBQ=%%s

in your qgis.bat / qgis-grass7.bat / qgis-ltr.bat / qgis-ltr-grass7.bat before the last line, that usually is something like

start "QGIS" /B "%OSGEO4W_ROOT%"binqqis...

[note that there are two percent signs in the value of PGEO_DRIVER_TEMPLATE variable]

Method 2 (works with QGIS 3)

In QGIS Settings panel -> Options | System | Environment add the following two variables:

variable name: OGR_SKIP 
value: ODBC

variable name: PGEO_DRIVER_TEMPLATE 
value: DRIVER=Microsoft Access Driver (*.mdb, *.accdb);DBQ=%s

and check the "Use custom variables" checkbox

[note that in this case there is only one percent sign in the value of PGEO_DRIVER_TEMPLATE variable]

Method 3 (works with both QGIS 2 and QGIS 3)

In the Environment Variables panel of the Windows Advanced System Settings, set the following two new variables as User Variables or System Variables:

variable name: OGR_SKIP 
value: ODBC

variable name: PGEO_DRIVER_TEMPLATE 
value: DRIVER=Microsoft Access Driver (*.mdb, *.accdb);DBQ=%s

[note that also in this case there is only one percent sign in the value of PGEO_DRIVER_TEMPLATE variable]